Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 20/20 | 0.67 |
| ▸ | F11 | P03951 | 19/20 | 0.67 |
| ▸ | F10 | P00742 | 17/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4674315 | 0.96 | F7 (0.69) | F7F11F10 | |
| SCHEMBL4675052 | 0.92 | F7 (0.68) | F7F11F10 | |
| SCHEMBL4734770 | 0.91 | F7 (0.65) | F7F11F10 | |
| SCHEMBL4675561 | 0.90 | F7 (0.70) | F7F11F10 | |
| SCHEMBL4735584 | 0.90 | F11 (0.63) | F7F11F10 | |
| SCHEMBL4682668 | 0.88 | F11 (0.67) | F7F11F10 | |
| SCHEMBL4678677 | 0.88 | F11 (0.67) | F7F11F10 | |
| SCHEMBL4678730 | 0.88 | F7 (0.64) | F7F11F10 | |
| SCHEMBL4679029 | 0.88 | F7 (0.64) | F7F11F10 | |
| SCHEMBL4677398 | 0.87 | F11 (0.60) | F7F11F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601656-A4 | TETRAHYDROQUINOLINE DERIVATIVES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2008-06-11 | — | — | EP | claimed |
| EP-1601656-A1 | TETRAHYDROQUINOLINE DERIVATIVES USEFUL AS SERINE PROTEASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2005-12-07 | — | — | EP | claimed |
| WO-2004080971-A1 | TETRAHYDROQUINOLINE DERIVATIVES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-23 | — | — | WO | claimed |