Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.78 |
| ▸ | HTT | P42858 | 3/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | HPGD | P15428 | 6/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4201226 | 0.89 | KDM4E (0.98) | KDM4EHTTALDH1A1HPGDHSD17B10 | |
| SCHEMBL1718809 | 0.88 | KDM4E (1.00) | KDM4EHTTALDH1A1HPGDHSD17B10 | |
| SCHEMBL25430390 | 0.86 | KDM4E (0.96) | KDM4EHTTALDH1A1HPGDHSD17B10 | |
| SCHEMBL4211253 | 0.85 | KDM4E (0.66) | KDM4EHTTALDH1A1HPGDHSD17B10 | |
| SCHEMBL1718813 | 0.85 | KDM4E (0.74) | KDM4EHTTALDH1A1HPGDHSD17B10 | |
| SCHEMBL4204723 | 0.85 | KDM4E (0.66) | KDM4EHTTALDH1A1HPGDHSD17B10 | |
| SCHEMBL4215699 | 0.84 | KDM4E (0.77) | KDM4EHTTALDH1A1HPGDHSD17B10 | |
| SCHEMBL14366824 | 0.83 | KDM4E (0.76) | KDM4EHTTALDH1A1HPGDHSD17B10 | |
| SCHEMBL25969729 | 0.81 | KDM4E (0.66) | KDM4EHTTALDH1A1HPGDHSD17B10 | |
| SCHEMBL29152859 | 0.81 | KDM4E (0.69) | KDM4EHTTALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008056176-A1 | PYRAZOLOPYRIMIDINES AS PHOSPHODIESTERASE INHIBITORS | SCOTTISH BIOMEDICAL LIMITED (GB) | 2008-05-15 | — | — | WO | disclosed |