⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18379563 | 0.77 | CRBN (0.53) | — | |
| SCHEMBL570069 | 0.76 | — | — | |
| SCHEMBL12316475 | 0.76 | — | — | |
| SCHEMBL22106713 | 0.76 | — | — | |
| SCHEMBL19359454 | 0.76 | CRBN (0.42) | — | |
| SCHEMBL19359384 | 0.76 | CRBN (0.42) | — | |
| SCHEMBL11132566 | 0.74 | GAA (0.42) | — | |
| SCHEMBL11720185 | 0.74 | GAA (0.42) | — | |
| SCHEMBL6820081 | 0.73 | MAP3K14 (0.41) | — | |
| SCHEMBL19100106 | 0.73 | GAA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354786-B | Method for preparing difunctional polyether-ether-ketone by using mussel derived peptide and biological orthogonal reaction and application thereof | 苏州大学附属第一医院 | 2023-07-04 | — | — | CN | claimed |
| CN-113354786-A | Method for preparing difunctional polyether-ether-ketone by using mussel-derived peptide in combination with bioorthogonal reaction and application thereof | 苏州大学附属第一医院 | 2021-09-07 | — | — | CN | claimed |
| CN-113354786-B | Method for preparing difunctional polyether-ether-ketone by using mussel derived peptide and biological orthogonal reaction and application thereof | 苏州大学附属第一医院 | 2023-07-04 | — | — | CN | disclosed |
| CN-112423738-B | Nanoparticle complex for improving intracellular uptake efficiency by surface modification of lipid, and method for producing same | 西江大学校产学协力团 | 2023-06-20 | — | — | CN | disclosed |
| US-20220090026-A1 | VIRAL NANOPARTICLE MULTIMERS | UNIV CASE WESTERN RESERVE (US) | 2022-03-24 | — | — | US | disclosed |
| CN-114173768-A | Nanoparticle complex for treating diseases and method for producing same | 西江大学校产学协力团 | 2022-03-11 | — | — | CN | disclosed |
| US-11193111-B2 | Viral nanoparticle multimers | CASE WESTERN RESERVE UNIVERSITY (US) | 2021-12-07 | — | — | US | disclosed |
| CN-113354786-A | Method for preparing difunctional polyether-ether-ketone by using mussel-derived peptide in combination with bioorthogonal reaction and application thereof | 苏州大学附属第一医院 | 2021-09-07 | — | — | CN | disclosed |
| US-20210139873-A1 | RNA SILENCING NANOZYMES | NATIONAL SCIENCE FOUNDATION | 2021-05-13 | — | — | US | disclosed |
| CN-112423738-A | Nanoparticle complex for improving intracellular uptake efficiency by surface modification with lipid and method for producing same | 西江大学校产学协力团 | 2021-02-26 | — | — | CN | disclosed |
| WO-2020018739-A1 | RNA SILENCING NANOZYMES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2020-01-23 | — | — | WO | disclosed |
| US-20070065484-A1 | In situ occlusion using natural biodegradable polysaccharides | SURMODICS MD, LLC | 2007-03-22 | — | — | US | disclosed |
| EP-1755696-A1 | NATURAL BIODEGRADABLE POLYSACCHARIDE COATINGS FOR MEDICAL ARTICLES | SurModics, Inc. (US) | 2007-02-28 | — | — | EP | disclosed |
| US-20060194813-A1 | Indolinone derivatives substituted in the 6 position, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2006-08-31 | — | — | US | disclosed |
| WO-2005113034-A1 | NATURAL BIODEGRADABLE POLYSACCHARIDES COATINGS FOR MEDICAL ARTICLES | SURMODICS, INC. (US) | 2005-12-01 | — | — | WO | disclosed |
| US-20050255142-A1 | Coatings for medical articles including natural biodegradable polysaccharides | SURMODICS, INC. | 2005-11-17 | — | — | US | disclosed |
| US-6855710-B2 | Substituted indolines with an inhibitory effect on various kinases and complexes of CDKs | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2005-02-15 | — | — | US | disclosed |
| US-20050009898-A1 | New substituted indolinones, their manufacture and their use as medicaments | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-01-13 | — | — | US | disclosed |
| US-6794395-B1 | Substituted indolinones, their manufacture and their use as medicaments | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-09-21 | — | — | US | disclosed |
| US-20040058978-A1 | Novel substituted indolines with an inhibitory effect on various kinases and complexes of CDKs | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2004-03-25 | — | — | US | disclosed |