SCHEMBL11720185

SCHEMBL11720185

CC(=O)NC1CC(=O)NC1=O

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.42
TSHR P16473 1/20 0.42
CRBN Q96SW2 12/20 0.39
MAP3K14 Q99558 1/20 0.39
DDB1 Q16531 6/20 0.38
IKZF3 Q9UKT9 1/20 0.36
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
APOL1 O14791 2/20 0.34
PYGL P06737 1/20 0.34
PYGM P11217 1/20 0.34
MEN1 O00255 1/20 0.33
APEX1 P27695 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11132566 1.00 GAA (0.42) GAATSHRCRBNMAP3K14DDB1
SCHEMBL19359454 0.82 CRBN (0.42) GAATSHRCRBNMAP3K14DDB1
SCHEMBL19359238 0.82 CRBN (0.42) GAATSHRCRBNMAP3K14DDB1
SCHEMBL19359384 0.82 CRBN (0.42) GAATSHRCRBNMAP3K14DDB1
SCHEMBL444006 0.81 CRBN (0.58) CRBNDDB1IKZF3
SCHEMBL16798767 0.81 CRBN (0.58) CRBNDDB1IKZF3
SCHEMBL6600630 0.79 APOL1 (0.40) GAATSHRCRBNMAP3K14DDB1
SCHEMBL23513495 0.77 GAA (0.59) GAATSHRCRBNDDB1
SCHEMBL14277693 0.77 GAA (0.59) GAATSHRCRBNDDB1
SCHEMBL4760856 0.77 GAA (0.59) GAATSHRCRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4057432-A PHOTOGRAPHIC COUPLERS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-11-08 US disclosed