Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.57 |
| ▸ | ERBB2 | P04626 | 14/20 | 0.57 |
| ▸ | KDR | P35968 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1095343 | 0.85 | EGFR (0.62) | EGFRERBB2KDR | |
| SCHEMBL1105401 | 0.85 | EGFR (0.62) | EGFRERBB2KDR | |
| SCHEMBL1105400 | 0.83 | EGFR (0.60) | EGFRERBB2KDR | |
| SCHEMBL5317684 | 0.83 | EGFR (0.60) | EGFRERBB2KDR | |
| SCHEMBL1095955 | 0.83 | EGFR (0.60) | EGFRERBB2KDR | |
| SCHEMBL1105388 | 0.83 | EGFR (0.60) | EGFRERBB2KDR | |
| SCHEMBL1105375 | 0.83 | KDR (0.60) | EGFRERBB2KDR | |
| SCHEMBL1095957 | 0.83 | EGFR (0.60) | EGFRERBB2KDR | |
| SCHEMBL1096503 | 0.83 | EGFR (0.60) | EGFRERBB2KDR | |
| SCHEMBL4997605 | 0.83 | KDR (0.60) | EGFRERBB2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073519-A1 | PROCESS FOR PREPARING SUBSTITUTED DIAMINOPYRIMIDINE OXIMES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-06-19 | — | — | WO | disclosed |