Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 19/20 | 0.61 |
| ▸ | BACE2 | Q9Y5Z0 | 16/20 | 0.58 |
| ▸ | CTSD | P07339 | 13/20 | 0.58 |
| ▸ | REN | P00797 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737256 | 0.91 | BACE1 (0.62) | BACE1BACE2CTSDREN | |
| SCHEMBL4737201 | 0.87 | BACE1 (0.66) | BACE1BACE2CTSDREN | |
| SCHEMBL4738633 | 0.86 | BACE1 (0.48) | BACE1BACE2CTSDREN | |
| SCHEMBL4734540 | 0.85 | BACE1 (0.50) | BACE1BACE2CTSDREN | |
| SCHEMBL8173593 | 0.83 | BACE1 (0.65) | BACE1BACE2CTSDREN | |
| SCHEMBL5139737 | 0.81 | BACE1 (0.45) | BACE1BACE2CTSDREN | |
| SCHEMBL4783664 | 0.80 | BACE1 (0.60) | BACE1BACE2CTSDREN | |
| SCHEMBL4735526 | 0.78 | BACE1 (0.65) | BACE1BACE2CTSDREN | |
| SCHEMBL4785076 | 0.78 | BACE1 (0.78) | BACE1BACE2CTSDREN | |
| SCHEMBL8186155 | 0.77 | BACE1 (0.66) | BACE1BACE2CTSDREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076044-A1 | NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | claimed |