Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 16/20 | 0.78 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.54 |
| ▸ | BCL2 | P10415 | 12/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | BCL2L2 | Q92843 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737863 | 1.00 | BCL2L1 (0.78) | BCL2L1DOT1LBCL2POLBMAPT | |
| SCHEMBL2948219 | 0.88 | BCL2L1 (0.77) | BCL2L1DOT1LBCL2POLBMAPT | |
| SCHEMBL27671268 | 0.88 | BCL2L1 (0.89) | BCL2L1DOT1LBCL2BCL2L2ALB | |
| SCHEMBL1542046 | 0.88 | BCL2L1 (0.89) | BCL2L1DOT1LBCL2BCL2L2ALB | |
| SCHEMBL376632 | 0.87 | BCL2L1 (1.00) | BCL2L1BCL2BCL2L2ALB | |
| SCHEMBL29686481 | 0.87 | BCL2L1 (1.00) | BCL2L1BCL2BCL2L2ALB | |
| SCHEMBL31570834 | 0.87 | BCL2L1 (0.76) | BCL2L1DOT1LBCL2BCL2L2ALB | |
| SCHEMBL554723 | 0.87 | BCL2L1 (1.00) | BCL2L1BCL2BCL2L2ALB | |
| SCHEMBL1541685 | 0.87 | BCL2L1 (0.88) | BCL2L1DOT1LBCL2BCL2L2ALB | |
| SCHEMBL4733552 | 0.87 | BCL2L1 (0.88) | BCL2L1DOT1LBCL2BCL2L2ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221132-A1 | Multi-Functional Small Molecules as Anti-Proliferative Agents | CURIS, INC. | 2008-09-11 | — | — | US | disclosed |
| WO-2008033747-A9 | MULTI-FUNCTIONAL SMALL MOLECULES AS ANTI-PROLIFERATIVE AGENTS | CURIS INC (MA) | 2008-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221132-A1 | Multi-Functional Small Molecules as Anti-Proliferative Agents | HDAC1, HDAC6, HDAC5 | BCL2L1 358/4885DOT1L 140/4885BCL2 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.