Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 10/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 8/20 | 0.51 |
| ▸ | ACVR1 | Q04771 | 5/20 | 0.51 |
| ▸ | WEE1 | P30291 | 3/20 | 0.50 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | STAT5A | P42229 | 1/20 | 0.42 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083936 | 0.87 | RIPK2 (0.65) | RIPK2NOD2ACVR1WEE1ABL1 | |
| SCHEMBL4738344 | 0.87 | RIPK2 (0.52) | RIPK2NOD2ACVR1WEE1ABL1 | |
| SCHEMBL30837130 | 0.84 | ABL1 (0.52) | RIPK2NOD2ACVR1WEE1ABL1 | |
| SCHEMBL20563978 | 0.84 | ABL1 (0.52) | RIPK2NOD2ACVR1WEE1ABL1 | |
| SCHEMBL31635921 | 0.82 | MAPK14 (0.40) | RIPK2NOD2ACVR1WEE1MAPK14 | |
| SCHEMBL20564935 | 0.81 | RIPK2 (0.66) | RIPK2NOD2ACVR1WEE1ABL1 | |
| SCHEMBL29498190 | 0.81 | RIPK2 (0.66) | RIPK2NOD2ACVR1WEE1ABL1 | |
| SCHEMBL20564708 | 0.81 | RIPK2 (0.66) | RIPK2NOD2ACVR1WEE1ABL1 | |
| SCHEMBL29498175 | 0.81 | RIPK2 (0.66) | RIPK2NOD2ACVR1WEE1ABL1 | |
| SCHEMBL4739074 | 0.81 | TNK2 (0.46) | ABL1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008078249-A1 | ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-07-03 | — | — | WO | disclosed |