Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 6/20 | 0.46 |
| ▸ | SIK2 | Q9H0K1 | 5/20 | 0.42 |
| ▸ | STK26 | Q9P289 | 2/20 | 0.42 |
| ▸ | STK4 | Q13043 | 1/20 | 0.42 |
| ▸ | STK3 | Q13188 | 1/20 | 0.42 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
| ▸ | PAK1 | Q13153 | 7/20 | 0.41 |
| ▸ | SIK1 | P57059 | 4/20 | 0.39 |
| ▸ | SIK3 | Q9Y2K2 | 4/20 | 0.39 |
| ▸ | PAK2 | Q13177 | 2/20 | 0.39 |
| ▸ | PAK3 | O75914 | 1/20 | 0.39 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | MELK | Q14680 | 1/20 | 0.39 |
| ▸ | PKN3 | Q6P5Z2 | 1/20 | 0.39 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.39 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4182680 | 0.89 | TNK2 (0.46) | TNK2SIK2STK26STK4STK3 | |
| SCHEMBL4738003 | 0.81 | RIPK2 (0.51) | SRCABL1 | |
| SCHEMBL4178516 | 0.76 | TNK2 (0.48) | TNK2SIK2STK26STK4STK3 | |
| SCHEMBL1060740 | 0.73 | MERTK (0.38) | GNRHR | |
| SCHEMBL20564687 | 0.72 | BTK (0.50) | SRCBTKLYN | |
| SCHEMBL4169067 | 0.71 | TNK2 (0.45) | TNK2SIK2STK26STK4STK3 | |
| SCHEMBL27265461 | 0.71 | USP30 (0.42) | TNK2SRCLYN | |
| SCHEMBL4091072 | 0.71 | RIPK2 (0.48) | TNK2SIK2PAK1SIK1SIK3 | |
| SCHEMBL4181003 | 0.71 | PAK1 (0.51) | TNK2SIK2STK26STK4STK3 | |
| SCHEMBL20564688 | 0.70 | RIPK2 (0.51) | SIK2STK26STK4STK3STK24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008078249-A1 | ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-07-03 | — | — | WO | disclosed |