⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014793 | 0.75 | — | — | |
| SCHEMBL2834452 | 0.73 | — | — | |
| SCHEMBL18628735 | 0.72 | — | — | |
| SCHEMBL6962823 | 0.69 | — | — | |
| SCHEMBL6236803 | 0.68 | FBP1 (0.42) | — | |
| SCHEMBL15948451 | 0.68 | — | — | |
| SCHEMBL65108 | 0.67 | — | — | |
| SCHEMBL27150056 | 0.65 | — | — | |
| SCHEMBL7715835 | 0.65 | — | — | |
| Iodide SCHEMBL27655122 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085119-A1 | NEW PYRIDINE ANALOGUES VIII 518 | ASTRAZENECA AB (SE) | 2008-07-17 | — | — | WO | disclosed |
| US-5378847-A | Cyclization by forming a bond between carbon and nitrogen, reaction with formaldehyde and amine | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1995-01-03 | — | — | US | disclosed |
| US-5296609-A | Antiischemic agents | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1994-03-22 | — | — | US | disclosed |