Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.78 |
| ▸ | NPC1 | O15118 | 6/20 | 0.67 |
| ▸ | CA12 | O43570 | 2/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.64 |
| ▸ | CA2 | P00918 | 2/20 | 0.64 |
| ▸ | CA9 | Q16790 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 5/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735887 | 0.88 | RAB9A (0.93) | RAB9ANPC1CA12CA1CA2 | |
| SCHEMBL4737060 | 0.88 | RAB9A (1.00) | RAB9ANPC1CA12CA1CA2 | |
| SCHEMBL4739304 | 0.84 | RAB9A (0.78) | RAB9ANPC1CA12CA1CA2 | |
| SCHEMBL4738902 | 0.84 | RAB9A (0.78) | RAB9ANPC1CA12CA1CA2 | |
| SCHEMBL4736959 | 0.84 | RAB9A (0.88) | RAB9ANPC1CA12CA1CA2 | |
| SCHEMBL4739354 | 0.84 | RAB9A (0.78) | RAB9ANPC1CA12CA1CA2 | |
| SCHEMBL4474345 | 0.81 | CA12 (0.61) | RAB9ANPC1CA12CA1CA2 | |
| SCHEMBL4787183 | 0.80 | KMT2A (0.89) | RAB9ANPC1CA12CA1CA2 | |
| SCHEMBL4784413 | 0.80 | RAB9A (0.71) | RAB9ANPC1CA12CA1CA2 | |
| SCHEMBL4740266 | 0.80 | RAB9A (0.71) | RAB9ANPC1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | claimed |
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |