⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8158 | 0.85 | ALDH1A1 (1.00) | — | |
| SCHEMBL30568759 | 0.85 | ALDH1A1 (1.00) | — | |
| SCHEMBL7662969 | 0.84 | ALDH1A1 (0.52) | — | |
| Acetic Acid SCHEMBL27748569 | 0.83 | ALDH1A1 (0.83) | — | |
| SCHEMBL24421 | 0.83 | — | — | |
| SCHEMBL10640242 | 0.82 | ALDH1A1 (0.94) | — | |
| SCHEMBL17477083 | 0.82 | ALDH1A1 (0.94) | — | |
| Methyl Alcohol SCHEMBL27968813 | 0.82 | ALDH1A1 (0.94) | — | |
| SCHEMBL9556715 | 0.82 | ALDH1A1 (0.94) | — | |
| SCHEMBL28174826 | 0.82 | ALDH1A1 (0.94) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023063154-A1 | TRACER COMPOSITION FOR RADIOACTIVE PET DIAGNOSIS, INTERMEDIATE THEREOF, AND PRODUCTION METHOD THEREOF | 国立大学法人大阪大学 | 2023-04-20 | — | — | WO | disclosed |
| EP-3527552-B1 | FUSED TRICYCLIC GAMMA-AMINO ACID DERIVATIVE, PREPARATION METHOD THEREFORE, AND MEDICAL USE THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO LTD (CN) | 2022-11-30 | — | — | EP | disclosed |
| CN-109195945-B | Fused tricyclic gamma-amino acid derivative, preparation method and application thereof in medicine | 四川海思科制药有限公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-113316564-A | Fused tricyclic deuterated derivative, composition and application thereof | 四川海思科制药有限公司 | 2021-08-27 | — | — | CN | disclosed |
| CN-107848953-B | Fused ring gamma-amino acid derivative, preparation method and application thereof in medicine | 四川海思科制药有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-107848952-B | Fused tricyclic gamma-amino acid derivative, preparation method and application thereof in medicine | 四川海思科制药有限公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-106928080-B | Fused ring gamma-amino acid derivative, preparation method and application thereof in medicine | 四川海思科制药有限公司 | 2020-12-25 | — | — | CN | disclosed |
| CN-106928081-B | Fused ring gamma-amino acid derivative, preparation method and application thereof in medicine | 四川海思科制药有限公司 | 2020-12-15 | — | — | CN | disclosed |
| WO-2020155953-A1 | FUSED TRICYCLIC DEUTERATED DERIVATIVE, COMPOSITION AND USE THEREOF | 四川海思科制药有限公司 | 2020-08-06 | — | — | WO | disclosed |
| US-10654794-B2 | Fused tricyclic Γ-amino acid derivative, preparation method therefor, and medical use thereof | SICHUAN HAISO PHARMACEUTICAL CO., LTD. (CN) | 2020-05-19 | — | — | US | disclosed |
| US-8324425-B2 | Method for producing bicyclic γ-amino acid derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20120071685-A1 | METHOD FOR PRODUCING BICYCLIC gamma-AMINO ACID DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-22 | — | — | US | disclosed |
| EP-2412700-A1 | METHOD FOR PRODUCING BICYCLIC GAMMA-AMINO ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2012-02-01 | — | — | EP | disclosed |
| US-7947738-B2 | Bicyclic γ-amino acid derivative | DAIICHI SANKYO COMPANY, LTD. (JP) | 2011-05-24 | — | — | US | disclosed |
| US-20100249229-A1 | BICYCLIC gamma-AMINO ACID DERIVATIVE | DAIICHI SANKYO COMPANY, LTD. (JP) | 2010-09-30 | — | — | US | disclosed |
| EP-2192109-A1 | BICYCLIC -AMINO ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-06-02 | — | — | EP | disclosed |
| US-5102997-A | Antibiotics | SANKYO COMPANY LIMITED (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0300423-A2 | Cephalosporin compound, method of its production and composition for prevention and treatment of bacterial infectious diseases | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1989-01-25 | — | — | EP | disclosed |
| EP-0160391-A1 | Carbapenem derivatives and compositions containing them | SANKYO COMPANY LIMITED (JP) | 1985-11-06 | — | — | EP | disclosed |
| EP-0065745-A3 | SYN-ISOMERS OF 7-SUBSTITUTED-3-CEPHEM-4-CARBOXYLIC ACID ESTERS, AND A PROCESS FOR PRODUCTION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-12-14 | — | — | EP | disclosed |