Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.62 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737633 | 0.89 | SLC40A1 (0.49) | SLC40A1FFAR4MEN1KMT2AGAA | |
| SCHEMBL4736358 | 0.87 | FFAR4 (0.48) | SLC40A1FFAR4MEN1KMT2ALMNA | |
| SCHEMBL4736750 | 0.85 | SLC40A1 (0.67) | SLC40A1FFAR4MEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL4738764 | 0.77 | SLC40A1 (0.57) | SLC40A1FFAR4MEN1KMT2ANPC1 | |
| SCHEMBL11973810 | 0.77 | SLC40A1 (1.00) | SLC40A1MEN1KMT2ANPC1HSP90AA1 | |
| SCHEMBL4739194 | 0.76 | SLC40A1 (0.55) | SLC40A1FFAR4MEN1KMT2ALMNA | |
| SCHEMBL4736820 | 0.74 | FFAR4 (0.54) | SLC40A1FFAR4MEN1KMT2AALDH1A1 | |
| SCHEMBL26053590 | 0.72 | KMT2A (0.72) | SLC40A1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11997125 | 0.71 | SLC40A1 (0.84) | SLC40A1MEN1KMT2ANPC1HSP90AA1 | |
| SCHEMBL3819661 | 0.68 | MAPT (0.58) | MEN1KMT2AHSP90AA1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008074068-A1 | SUBSTITUTED QUINOLINE DERIVATIVES AS ANTIAMYLOIDOGENEIC AGENTS | PRANA BIOTECHNOLOGY LIMITED (AU) | 2008-06-26 | — | — | WO | disclosed |