Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | TP53 | P04637 | 4/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.53 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.51 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4738976 | 0.99 | RAB9A (0.64) | RAB9ASMN1; SMN2NPC1TP53ALOX15 | |
| SCHEMBL16554592 | 0.80 | MAPT (0.48) | RAB9ASMN1; SMN2NPC1TP53ALOX15 | |
| SCHEMBL3142490 | 0.79 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1TP53ALOX15 | |
| SCHEMBL18470910 | 0.79 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1TP53ALOX15 | |
| SCHEMBL12395356 | 0.76 | HDAC6 (0.61) | MAPT | |
| SCHEMBL4735305 | 0.75 | HDAC3 (0.56) | RAB9ASMN1; SMN2NPC1TP53ALOX15 | |
| SCHEMBL1663960 | 0.75 | MAPT (0.60) | RAB9ASMN1; SMN2NPC1MAPK1HTT | |
| SCHEMBL13930689 | 0.75 | MAPT (0.70) | RAB9ASMN1; SMN2NPC1TP53ALOX15 | |
| SCHEMBL16436048 | 0.75 | PTPN1 (0.61) | RAB9ASMN1; SMN2NPC1ALDH1A1KMT2A | |
| SCHEMBL16436052 | 0.75 | KCNQ3 (0.65) | RAB9ASMN1; SMN2NPC1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |