Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | CDC25A | P30304 | 2/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | POLA1 | P09884 | 1/20 | 0.53 |
| ▸ | ST6GAL1 | P15907 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739139 | 0.91 | CDC25A (0.59) | VDRUSP2CDC25AABCC4POLA1 | |
| SCHEMBL13017807 | 0.91 | VDR (0.56) | VDRUSP2CDC25AABCC4POLA1 | |
| SCHEMBL4740075 | 0.91 | VDR (0.56) | VDRUSP2CDC25AABCC4POLA1 | |
| SCHEMBL21927842 | 0.90 | VDR (0.57) | VDRUSP2CDC25AABCC4POLA1 | |
| SCHEMBL4739495 | 0.89 | VDR (0.57) | VDRUSP2CDC25AABCC4POLA1 | |
| SCHEMBL4739243 | 0.88 | CDC25A (0.58) | VDRUSP2CDC25AABCC4POLA1 | |
| SCHEMBL4738713 | 0.88 | VDR (0.53) | VDRUSP2CDC25AABCC4POLA1 | |
| SCHEMBL4734583 | 0.88 | CDC25A (0.56) | VDRUSP2CDC25AABCC4POLA1 | |
| SCHEMBL24015370 | 0.87 | VDR (0.55) | VDRUSP2CDC25AABCC4POLA1 | |
| SCHEMBL25819491 | 0.86 | CYP2C19 (0.53) | VDRUSP2ST6GAL1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077247-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES COMPRISING CHOLESTEROL | MIV THERAPEUTICS INC. (CA) | 2008-07-03 | — | — | WO | disclosed |