Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.85 |
| ▸ | HTT | P42858 | 3/20 | 0.85 |
| ▸ | PPARG | P37231 | 3/20 | 0.85 |
| ▸ | NCOA2 | Q15596 | 3/20 | 0.85 |
| ▸ | NCOA1 | Q15788 | 3/20 | 0.85 |
| ▸ | NCOA3 | Q9Y6Q9 | 3/20 | 0.85 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.85 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.85 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.85 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.59 |
| ▸ | LSS | P48449 | 1/20 | 0.57 |
| ▸ | GALR3 | O60755 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733214 | 0.98 | MEN1 (0.88) | MEN1KMT2AHTTPPARGNCOA2 | |
| SCHEMBL10724383 | 0.93 | MEN1 (0.74) | MEN1KMT2AHTTPPARGNCOA2 | |
| SCHEMBL4737776 | 0.92 | MEN1 (0.72) | MEN1KMT2AHTTPPARGNCOA2 | |
| SCHEMBL9811673 | 0.92 | HTT (0.76) | MEN1KMT2AHTTPPARGNCOA2 | |
| SCHEMBL4737165 | 0.90 | HTT (0.78) | MEN1KMT2AHTTPPARGNCOA2 | |
| SCHEMBL4734648 | 0.89 | HTT (0.72) | MEN1KMT2AHTTPPARGNCOA2 | |
| SCHEMBL4735808 | 0.88 | MEN1 (0.74) | MEN1KMT2AHTTPPARGNCOA2 | |
| SCHEMBL14517805 | 0.87 | HTT (0.69) | MEN1KMT2AHTTPPARGNCOA2 | |
| SCHEMBL14407886 | 0.87 | MEN1 (0.64) | MEN1KMT2AHTTPPARGNCOA2 | |
| SCHEMBL4734772 | 0.87 | MEN1 (0.83) | MEN1KMT2AHTTPPARGNCOA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008069518-A1 | PHARMACEUTICAL COMPOSITION FOR CONTROLLING THE FUNCTION OF SPIHNGOSYLPHOSPHORYLCHOLINE | AMOREPACIFIC CORPORATION (KR) | 2008-06-12 | — | — | WO | disclosed |