Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | PPARG | P37231 | 3/20 | 0.76 |
| ▸ | NCOA2 | Q15596 | 3/20 | 0.76 |
| ▸ | NCOA1 | Q15788 | 3/20 | 0.76 |
| ▸ | NCOA3 | Q9Y6Q9 | 3/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.76 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.76 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.54 |
| ▸ | LSS | P48449 | 1/20 | 0.53 |
| ▸ | GALR3 | O60755 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733214 | 0.93 | MEN1 (0.88) | HTTMEN1KMT2APPARGNCOA2 | |
| SCHEMBL14517805 | 0.92 | HTT (0.69) | HTTMEN1KMT2APPARGNCOA2 | |
| SCHEMBL4738845 | 0.92 | MEN1 (0.85) | HTTMEN1KMT2APPARGNCOA2 | |
| SCHEMBL10724383 | 0.85 | MEN1 (0.74) | HTTMEN1KMT2APPARGNCOA2 | |
| SCHEMBL4737165 | 0.85 | HTT (0.78) | HTTMEN1KMT2APPARGNCOA2 | |
| SCHEMBL4734648 | 0.84 | HTT (0.72) | HTTMEN1KMT2APPARGNCOA2 | |
| SCHEMBL4737776 | 0.84 | MEN1 (0.72) | HTTMEN1KMT2APPARGNCOA2 | |
| SCHEMBL4735808 | 0.83 | MEN1 (0.74) | HTTMEN1KMT2APPARGNCOA2 | |
| SCHEMBL29177626 | 0.82 | SMN1; SMN2 (0.63) | HTTMEN1KMT2APPARGNCOA2 | |
| SCHEMBL8624077 | 0.82 | MEN1 (0.78) | HTTMEN1KMT2APPARGNCOA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064861-A | ACYLATED AMINE COMPOUNDS WHICH ARE USEFUL FUNGICIGAL AGENTS | ROUSSEL UCLAF (FR) | 1991-11-12 | — | — | US | disclosed |