Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 4/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.69 |
| ▸ | ALDH3A1 | P30838 | 10/20 | 0.69 |
| ▸ | ALDH2 | P05091 | 9/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | ACHE | P22303 | 2/20 | 0.64 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30774299 | 1.00 | PARK7 (0.82) | PARK7ALDH1A1ALDH3A1ALDH2TP53 | |
| SCHEMBL22589373 | 0.91 | PARK7 (0.78) | PARK7ALDH1A1ALDH3A1ALDH2TP53 | |
| SCHEMBL4738025 | 0.91 | PARK7 (0.78) | PARK7ALDH1A1ALDH3A1ALDH2TP53 | |
| SCHEMBL4739934 | 0.90 | PARK7 (0.76) | PARK7ALDH1A1ALDH3A1ALDH2TP53 | |
| SCHEMBL4736390 | 0.90 | PARK7 (1.00) | PARK7ALDH1A1ALDH3A1ALDH2TP53 | |
| SCHEMBL20874420 | 0.90 | PARK7 (0.80) | PARK7ALDH1A1ALDH3A1ALDH2TP53 | |
| SCHEMBL4736331 | 0.90 | PARK7 (0.75) | PARK7ALDH1A1ALDH3A1ALDH2TP53 | |
| SCHEMBL4734658 | 0.88 | PARK7 (0.72) | PARK7ALDH1A1ALDH3A1ALDH2TP53 | |
| SCHEMBL4734272 | 0.86 | PARK7 (1.00) | PARK7ALDH1A1ALDH3A1ALDH2TP53 | |
| SCHEMBL4735921 | 0.86 | PARK7 (1.00) | PARK7ALDH1A1ALDH3A1ALDH2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486780-A | 1-benzyl isatin derivative and preparation method and application thereof | 武汉大学人民医院（湖北省人民医院） | 2024-02-02 | — | — | CN | disclosed |
| WO-2008074078-A1 | SELECTIVELY DELIVERABLE ISATIN-BASED CYTOTOXIC AGENTS | UNIVERSITY OF WOLLONGONG (AU) | 2008-06-26 | — | — | WO | disclosed |