Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.46 |
| ▸ | CCR9 | P51686 | 10/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739981 | 0.89 | EGLN3 (0.56) | EGLN3CCR9MEN1KMT2AFBP1 | |
| SCHEMBL4737534 | 0.88 | EGLN3 (0.44) | EGLN3CCR9MEN1KMT2AFBP1 | |
| SCHEMBL4741832 | 0.88 | CCR9 (0.44) | EGLN3CCR9MEN1KMT2AFBP1 | |
| SCHEMBL4782916 | 0.86 | CCR9 (0.43) | EGLN3CCR9MEN1KMT2ATP53 | |
| SCHEMBL4741831 | 0.86 | EGLN3 (0.48) | EGLN3CCR9MEN1KMT2A | |
| SCHEMBL4740088 | 0.85 | CCR9 (0.45) | EGLN3CCR9MEN1KMT2ATP53 | |
| SCHEMBL5000326 | 0.84 | CCR9 (0.47) | EGLN3CCR9MEN1KMT2ATP53 | |
| SCHEMBL4740335 | 0.84 | EGLN3 (0.46) | EGLN3CCR9MEN1KMT2A | |
| SCHEMBL4737518 | 0.83 | EGLN3 (0.51) | EGLN3CCR9MEN1KMT2A | |
| SCHEMBL4739991 | 0.82 | CCR9 (0.49) | EGLN3CCR9MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089051-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES: PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-24 | — | — | WO | disclosed |