Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 10/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740385 | 0.90 | CCR9 (0.45) | CCR9KMT2AMEN1METAP2ALDH1A1 | |
| SCHEMBL4737051 | 0.87 | BCL2 (0.55) | KMT2AMEN1BCL2MCL1SMN1; SMN2 | |
| SCHEMBL4737518 | 0.86 | EGLN3 (0.51) | CCR9KMT2AMEN1ALDH1A1EGLN3 | |
| SCHEMBL4741837 | 0.85 | CCR9 (0.42) | CCR9KMT2AMEN1SMN1; SMN2METAP2 | |
| SCHEMBL4739209 | 0.84 | EGLN3 (0.46) | CCR9KMT2AMEN1SMN1; SMN2TP53 | |
| SCHEMBL4739127 | 0.84 | KMT2A (0.44) | CCR9KMT2AMEN1SMN1; SMN2TP53 | |
| SCHEMBL4739981 | 0.83 | EGLN3 (0.56) | CCR9KMT2AMEN1SMN1; SMN2TP53 | |
| SCHEMBL4739991 | 0.83 | CCR9 (0.49) | CCR9KMT2AMEN1SMN1; SMN2TP53 | |
| SCHEMBL4741832 | 0.82 | CCR9 (0.44) | CCR9KMT2AMEN1SMN1; SMN2TP53 | |
| SCHEMBL4737534 | 0.82 | EGLN3 (0.44) | CCR9KMT2AMEN1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080171756-A1 | N-Substituted Glycine Derivatives: Prolyl Hydroxylase Inhibitors | SMITHKLINE BEECHAM CORPORATION | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171756-A1 | N-Substituted Glycine Derivatives: Prolyl Hydroxylase Inhibitors | HIF1AN, EGLN2, EGLN3 | CCR9 4560/4885KMT2A 734/4885MEN1 2935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.