Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 3/20 | 0.61 |
| ▸ | POLA1 | P09884 | 1/20 | 0.61 |
| ▸ | VDR | P11473 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.53 |
| ▸ | ST6GAL1 | P15907 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739235 | 0.92 | CDC25A (0.61) | CDC25APOLA1VDRUSP2CYP2D6 | |
| SCHEMBL4739243 | 0.89 | CDC25A (0.58) | CDC25APOLA1VDRUSP2CYP2D6 | |
| SCHEMBL4735348 | 0.89 | CDC25A (0.58) | CDC25APOLA1VDRUSP2CYP2D6 | |
| SCHEMBL4735216 | 0.88 | CDC25A (0.77) | CDC25APOLA1VDRUSP2CYP2D6 | |
| SCHEMBL4735308 | 0.88 | VDR (0.58) | CDC25APOLA1VDRUSP2CYP2D6 | |
| SCHEMBL21928679 | 0.87 | VDR (0.60) | CDC25APOLA1VDRUSP2ABCC4 | |
| SCHEMBL4739495 | 0.87 | VDR (0.57) | CDC25APOLA1VDRUSP2CYP2D6 | |
| SCHEMBL4740584 | 0.85 | VDR (0.56) | CDC25APOLA1VDRUSP2CYP2D6 | |
| SCHEMBL29578640 | 0.85 | CDC25A (0.57) | CDC25APOLA1VDRUSP2CYP2D6 | |
| SCHEMBL10017499 | 0.85 | CDC25A (0.68) | CDC25APOLA1VDRUSP2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077247-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES COMPRISING CHOLESTEROL | MIV THERAPEUTICS INC. (CA) | 2008-07-03 | — | — | WO | disclosed |