Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MC4R | P32245 | 8/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | AKT2 | P31751 | 1/20 | 0.48 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739742 | 1.00 | HDAC8 (0.54) | HDAC8HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL14615411 | 0.81 | HDAC8 (0.49) | HDAC8HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL1748434 | 0.78 | DPP4 (0.49) | HDAC8HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL1748433 | 0.78 | DPP4 (0.49) | HDAC8HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL3792052 | 0.78 | HDAC8 (0.70) | HDAC8HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL3792055 | 0.78 | HDAC8 (0.70) | HDAC8HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL1748779 | 0.78 | DPP4 (0.48) | HDAC8HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL1748778 | 0.78 | DPP4 (0.48) | HDAC8HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL4778879 | 0.78 | DPP4 (0.48) | HDAC8HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL4778870 | 0.78 | DPP4 (0.48) | HDAC8HDAC1HDAC3HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008090357-A2 | N, N; -SUBSTITUTED PIPERAZINES BINDING TO MELANOCORTIN RECEPTOR | PALATIN TECHNOLOGIES, INC. (US) | 2008-07-31 | — | — | WO | disclosed |