Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.52 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | GRK5 | P34947 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18433935 | 0.85 | HCAR3 (0.55) | AOC3HCAR3GBA1PARP10NNMT | |
| Hydrochloric Acid SCHEMBL5013471 | 0.83 | HCAR3 (0.54) | AOC3HCAR3GBA1PARP10NNMT | |
| SCHEMBL14534877 | 0.75 | HCAR3 (0.58) | AOC3HCAR3GBA1KMT2A | |
| SCHEMBL17316532 | 0.74 | AOC3 (0.58) | AOC3HCAR3GBA1CACNA1H | |
| SCHEMBL7134591 | 0.74 | PLA2G10 (0.83) | PLA2G10PLA2G2ACYP17A1PARP10KMT2A | |
| SCHEMBL13611416 | 0.73 | HCAR3 (0.76) | AOC3HCAR3GBA1 | |
| SCHEMBL856704 | 0.73 | GBA1 (0.56) | AOC3KLKB1KLK1HCAR3GBA1 | |
| SCHEMBL16274790 | 0.73 | GBA1 (0.56) | AOC3KLKB1KLK1HCAR3GBA1 | |
| SCHEMBL30175373 | 0.72 | GBA1 (0.60) | AOC3HCAR3GBA1CACNA1H | |
| SCHEMBL8430068 | 0.72 | GBA1 (0.60) | AOC3HCAR3GBA1CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |