Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 13/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 13/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 13/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 12/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 10/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1109790 | 1.00 | CHRM3 (0.41) | CHRM3POLBCHRM2CHRM1CHRM4 | |
| SCHEMBL1109782 | 1.00 | CHRM3 (0.41) | CHRM3POLBCHRM2CHRM1CHRM4 | |
| SCHEMBL3225415 | 1.00 | CHRM3 (0.41) | CHRM3POLBCHRM2CHRM1CHRM4 | |
| SCHEMBL1109780 | 1.00 | CHRM3 (0.41) | CHRM3POLBCHRM2CHRM1CHRM4 | |
| SCHEMBL1109822 | 0.99 | ALDH1A1 (0.40) | CHRM3POLBCHRM2CHRM1CHRM4 | |
| SCHEMBL3218882 | 0.99 | ALDH1A1 (0.40) | CHRM3POLBCHRM2CHRM1CHRM4 | |
| SCHEMBL13329443 | 0.99 | ALDH1A1 (0.40) | CHRM3POLBCHRM2CHRM1CHRM4 | |
| SCHEMBL3202857 | 0.96 | ATM (0.39) | CHRM3POLBCHRM2CHRM1CHRM4 | |
| SCHEMBL1109856 | 0.88 | POLB (0.44) | CHRM3POLBCHRM2CHRM1CHRM4 | |
| SCHEMBL1109796 | 0.87 | CHRM3 (0.39) | CHRM3CHRM2CHRM1CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |