Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.70 |
| ▸ | ITGAV | P06756 | 20/20 | 0.70 |
| ▸ | ITGB1 | P05556 | 18/20 | 0.70 |
| ▸ | ITGA5 | P08648 | 18/20 | 0.70 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.57 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067570 | 0.90 | ITGB3 (0.66) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL14104055 | 0.90 | ITGB3 (0.66) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL4069905 | 0.89 | ITGB3 (0.68) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| Hydrochloric Acid SCHEMBL4193237 | 0.89 | ITGB3 (0.64) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL13908271 | 0.86 | ITGB3 (0.82) | ITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL6174944 | 0.85 | ITGB3 (0.76) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL6177494 | 0.84 | ITGB3 (0.78) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL4742898 | 0.83 | ITGB3 (0.78) | ITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL4743165 | 0.83 | ITGB3 (0.78) | ITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL4065491 | 0.83 | ITGB3 (0.66) | ITGB3ITGAVITGB1ITGA5ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093064-A1 | L-ALANINE DERIVATIVES AS α5 BETA 1 ANTAGONISTS | ASTRAZENECA AB (SE) | 2008-08-07 | — | — | WO | disclosed |