Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9671249 | 0.89 | SLC2A1 (0.47) | NPC1RAB9APOLBALDH1A1SLC2A1 | |
| SCHEMBL5172043 | 0.86 | POLB (0.56) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL9808095 | 0.86 | NPC1 (0.55) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL28435021 | 0.84 | POLB (0.54) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL5169781 | 0.84 | POLB (0.54) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL10391283 | 0.84 | NPC1 (0.40) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL5168911 | 0.81 | NPC1 (0.65) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL424971 | 0.80 | HPGD (0.56) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL9672124 | 0.79 | SLC2A1 (0.44) | POLBALDH1A1SLC2A1KDM4E | |
| SCHEMBL10281202 | 0.79 | NPC1 (0.34) | NPC1RAB9APOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096128-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES 2 | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008096128-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES 2 | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |