SCHEMBL5168911

SCHEMBL5168911

Cc1ccc(SCCSc2ccc(C)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.65
RAB9A P51151 2/20 0.65
ALDH1A1 P00352 6/20 0.55
MAPT P10636 1/20 0.55
MAPK1 P28482 2/20 0.52
HPGD P15428 7/20 0.50
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
ACHE P22303 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
DRD2 P14416 1/20 0.46
DRD4 P21917 1/20 0.46
POLB P06746 1/20 0.46
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22755712 0.90 NPC1 (0.57) NPC1RAB9AALDH1A1MAPTMAPK1
SCHEMBL5171094 0.90 ALDH1A1 (0.71) NPC1RAB9AALDH1A1MAPTMAPK1
SCHEMBL9808095 0.89 NPC1 (0.55) NPC1RAB9AALDH1A1MAPTHPGD
SCHEMBL5172043 0.89 POLB (0.56) NPC1RAB9AALDH1A1MAPTHPGD
SCHEMBL5169781 0.87 POLB (0.54) NPC1RAB9AALDH1A1MAPTHPGD
SCHEMBL28435021 0.87 POLB (0.54) NPC1RAB9AALDH1A1MAPTHPGD
SCHEMBL8362962 0.87 NPC1 (0.53) NPC1RAB9AALDH1A1MAPTMAPK1
SCHEMBL15489110 0.86 ALDH1A1 (0.59) NPC1RAB9AALDH1A1MAPTMAPK1
SCHEMBL9770471 0.85 TDP1 (0.53) NPC1RAB9AALDH1A1MAPTMAPK1
SCHEMBL22755713 0.85 NPC1 (0.52) NPC1RAB9AALDH1A1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114685331-B Process for producing 1, 2-dithioethane compound 华南理工大学 2024-07-09 CN disclosed
CN-117567331-A Synthesis method of 1, 2-dithioethane compound and 1, 4-dithiane 河北北方学院 2024-02-20 CN disclosed
CN-114685331-A Process for producing 1, 2-dithioethane compound 华南理工大学 2022-07-01 CN disclosed
CN-112535277-A Oligosaccharide composition used as food ingredient and its preparation method 卡德纳生物股份有限公司 2021-03-23 CN disclosed
CN-112515178-A Oligosaccharide composition for nutritional composition and method for producing the same 卡德纳生物股份有限公司 2021-03-19 CN disclosed
CN-111471117-A Oligosaccharide composition and preparation method thereof 卡德纳生物有限公司 2020-07-31 CN disclosed
EP-1195259-B1 Sheet for ink jet-recording OJI PAPER CO (JP) 2007-04-25 EP disclosed
US-6852378-B2 Sheet for ink jet-recording OJI PAPER CO., LTD. (JP) 2005-02-08 US disclosed
US-20040058099-A1 Sheet for ink jet-recording OJI PAPER CO., LTD. 2004-03-25 US disclosed
EP-1195259-A2 Sheet for ink jet-recording OJI PAPER CO., LTD. (JP) 2002-04-10 EP disclosed
US-5773385-A Thermosensitive recording medium RICOH CO., LTD. (JP) 1998-06-30 US disclosed
US-4985393-A Bis/hydroxyphenylthio/ Compounds KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1991-01-15 US disclosed
US-4981836-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1991-01-01 US disclosed
EP-0373561-A2 Heat sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-06-20 EP disclosed
EP-0222343-B1 RECORDING MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1990-04-11 EP disclosed
US-4835133-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-30 US disclosed
US-4833121-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-23 US disclosed
US-4792542-A CONTAINING AN AROMATIC SULFIDE FUJI PHOTO FILM CO., LTD. (JP) 1988-12-20 US disclosed
EP-0222343-A2 Recording material FUJI PHOTO FILM CO., LTD. (JP) 1987-05-20 EP disclosed