Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.81 |
| ▸ | LMNA | P02545 | 4/20 | 0.81 |
| ▸ | MAPT | P10636 | 3/20 | 0.81 |
| ▸ | TSHR | P16473 | 3/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.81 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylcarbamazine SCHEMBL37736 | 0.90 | KDM4E (1.00) | KDM4EALDH1A1LMNAMAPTTSHR | |
| Diethylcarbamazine SCHEMBL37735 | 0.87 | KDM4E (0.94) | KDM4EALDH1A1LMNAMAPTTSHR | |
| SCHEMBL30384961 | 0.77 | ALDH1A1 (0.60) | KDM4EALDH1A1LMNAMAPTTSHR | |
| SCHEMBL72953 | 0.77 | ALDH1A1 (0.60) | KDM4EALDH1A1LMNAMAPTTSHR | |
| Citric Acid SCHEMBL4292973 | 0.77 | ALDH1A1 (0.60) | KDM4EALDH1A1LMNAMAPTTSHR | |
| SCHEMBL433131 | 0.76 | ALDH1A1 (0.58) | KDM4EALDH1A1LMNAMAPTTSHR | |
| SCHEMBL16737228 | 0.76 | ALDH1A1 (0.58) | KDM4EALDH1A1LMNAMAPTTSHR | |
| Water SCHEMBL28164707 | 0.76 | ALDH1A1 (0.58) | KDM4EALDH1A1LMNAMAPTTSHR | |
| Ammonia Solution, Strong SCHEMBL29179739 | 0.76 | ALDH1A1 (0.58) | KDM4EALDH1A1LMNAMAPTTSHR | |
| SCHEMBL27981114 | 0.76 | ALDH1A1 (0.58) | KDM4EALDH1A1LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008082808-A1 | RAPIDLY DISINTEGRATING LOW FRIABILITY TABLETS COMPRISING CALCIUM CARBONATE | J.M. HUBER CORPORATION (US) | 2008-07-10 | — | — | WO | disclosed |
| WO-2008082809-A1 | RAPIDLY DISSOLVING TABLETS COMPRISING LOW SURFACE AREA CALCIUM PHOSPHATES | J.M. HUBER CORPORATION (US) | 2008-07-10 | — | — | WO | disclosed |