Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4742113 | 0.94 | NR3C1 (0.51) | NR3C1PGR | |
| SCHEMBL1141826 | 0.85 | NR3C1 (0.47) | NR3C1PGR | |
| SCHEMBL1141822 | 0.85 | NR3C1 (0.47) | NR3C1PGR | |
| SCHEMBL1142470 | 0.85 | NR3C1 (0.47) | NR3C1PGR | |
| SCHEMBL2446572 | 0.85 | NR3C1 (0.47) | NR3C1PGR | |
| SCHEMBL2484059 | 0.82 | NR3C1 (0.49) | NR3C1PGR | |
| SCHEMBL1142457 | 0.82 | NR3C1 (0.51) | NR3C1 | |
| SCHEMBL2452082 | 0.82 | NR3C1 (0.50) | NR3C1 | |
| SCHEMBL1142461 | 0.82 | NR3C1 (0.51) | NR3C1 | |
| SCHEMBL1142160 | 0.81 | NR3C1 (0.48) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896424-A2 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF | Bristol-Myers Squibb Company (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006138373-A2 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-12-28 | — | — | WO | disclosed |