Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.47 |
| ▸ | GLUL | P15104 | 3/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1142038 | 0.81 | NR3C1 (0.48) | NR3C1GLULPGR | |
| SCHEMBL1142040 | 0.81 | NR3C1 (0.48) | NR3C1GLULPGR | |
| SCHEMBL1141869 | 0.80 | NR3C1 (0.57) | NR3C1PGR | |
| SCHEMBL1141864 | 0.80 | NR3C1 (0.57) | NR3C1PGR | |
| SCHEMBL1141870 | 0.80 | NR3C1 (0.57) | NR3C1PGR | |
| SCHEMBL1141919 | 0.79 | NR3C1 (0.45) | NR3C1GLULPGR | |
| SCHEMBL1141923 | 0.79 | NR3C1 (0.45) | NR3C1GLULPGR | |
| SCHEMBL1142284 | 0.79 | NR3C1 (0.60) | NR3C1GLULPGR | |
| SCHEMBL1142123 | 0.78 | NR3C1 (0.54) | NR3C1GLULPGR | |
| SCHEMBL1142125 | 0.78 | NR3C1 (0.54) | NR3C1GLULPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896424-A2 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF | Bristol-Myers Squibb Company (US) | 2008-03-12 | — | — | EP | claimed |
| WO-2006138373-A2 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-12-28 | — | — | WO | claimed |