⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798402 | 0.66 | KDM4E (0.36) | — | |
| SCHEMBL4078451 | 0.63 | — | — | |
| SCHEMBL4803476 | 0.61 | — | — | |
| SCHEMBL3928372 | 0.54 | — | — | |
| SCHEMBL3927845 | 0.49 | — | — | |
| SCHEMBL3928374 | 0.49 | — | — | |
| SCHEMBL3363217 | 0.49 | — | — | |
| SCHEMBL8926772 | 0.49 | — | — | |
| SCHEMBL2829995 | 0.48 | — | — | |
| SCHEMBL10707141 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957558-A2 | POLYARYLATE ACID CHLORIDE COMPOSITIONS AND DERIVATES THEREFROM | General Electric Company (US) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007070377-A2 | POLYARYLATE ACID CHLORIDE COMPOSITIONS AND DERIVATES THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2007-06-21 | — | — | WO | disclosed |
| US-20070135610-A1 | Polyarylate acid chloride compositions and derivatives therefrom | GENERAL ELECTRIC COMPANY (US) | 2007-06-14 | — | — | US | disclosed |
| EP-0182691-B1 | SUBSTITUTED THIOPHENE-2-SULFONAMIDES AND THEIR PREPARATION | MERCK & CO. INC. (US) | 1990-07-04 | — | — | EP | disclosed |
| EP-0155214-B1 | 2-SULFAMOYL-1H-INDOLE DERIVATIVES FOR THE TREATMENT OF ELEVATED INTRAOCULAR PRESSURE | MERCK & CO. INC. (US) | 1990-03-14 | — | — | EP | disclosed |
| EP-0129478-B1 | 2-SULFAMOYLBENZO (B) THIOPHENE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF ELEVATED INTRAOCULAR PRESSURE | MERCK & CO. INC. (US) | 1990-01-17 | — | — | EP | disclosed |
| EP-0221806-B1 | SUBSTITUTED THIOPHENE-2-SULFANOMIDE AND ANTIGLAUCOMA COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1990-01-10 | — | — | EP | disclosed |
| EP-0219429-B1 | SUBSTITUTED BENZENESULFONAMIDE AND ANTIGLAUCOMA FORMULATIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1989-12-20 | — | — | EP | disclosed |
| EP-0130109-B1 | DERIVATIVES OF THIOPHENESULFONAMIDE, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION FOR THE TOPICAL TREATMENT OF ELEVATED INTRAOCULAR PRESSURE | MERCK & CO. INC. (US) | 1989-09-13 | — | — | EP | disclosed |
| US-4840963-A | FOR GLAUCOMA | MERCK & CO., INC. (US) | 1989-06-20 | — | — | US | disclosed |
| EP-0122178-A2 | Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure | MERCK & CO. INC. (US) | 1984-10-17 | — | — | EP | disclosed |
| US-4477466-A | Acyloxy derivatives of [phenylsulfonyl(or sulfinyl)]thiophenesulfonamide for the topical treatment of elevated intraocular pressure | MERCK & CO., INC. (US) | 1984-10-16 | — | — | US | disclosed |
| US-4472418-A | Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure | MERCK & CO., INC. (US) | 1984-09-18 | — | — | US | disclosed |
| US-4472417-A | Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure | MERCK & CO., INC. (US) | 1984-09-18 | — | — | US | disclosed |
| US-4470991-A | Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure | MERCK & CO., INC. (US) | 1984-09-11 | — | — | US | disclosed |
| US-4456599-A | Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure | MERCK & CO., INC. (US) | 1984-06-26 | — | — | US | disclosed |
| US-4426388-A | 5-Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure | MERCK & CO., INC. (US) | 1984-01-17 | — | — | US | disclosed |
| US-4416890-A | GLAUCOMA TREATMENT | MERCK & CO., INC. (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0091367-A2 | Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure | MERCK & CO. INC. (US) | 1983-10-12 | — | — | EP | disclosed |
| EP-0070239-A1 | Benzothiazolesulfonamide derivatives, their preparation and ophthalmic compositions containing said derivatives | MERCK & CO. INC. (US) | 1983-01-19 | — | — | EP | disclosed |