Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 8/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4994580 | 0.88 | EGLN3 (0.49) | EGLN3EGLN1TP53EGLN2MEN1 | |
| SCHEMBL4738011 | 0.79 | EGLN3 (0.52) | EGLN3EGLN1TP53CYP2C19LMNA | |
| SCHEMBL4737678 | 0.75 | EGLN3 (0.48) | EGLN3EGLN1TP53EGLN2MEN1 | |
| SCHEMBL4992689 | 0.74 | EGLN3 (0.63) | EGLN3EGLN1TP53MEN1CYP2C9 | |
| SCHEMBL3423804 | 0.74 | EGLN3 (0.69) | EGLN3EGLN1TP53EGLN2MEN1 | |
| SCHEMBL15419450 | 0.73 | EGLN3 (0.58) | EGLN3EGLN1TP53EGLN2MEN1 | |
| SCHEMBL1641809 | 0.72 | EGLN3 (0.65) | EGLN3EGLN1EGLN2MEN1KMT2A | |
| SCHEMBL4739942 | 0.72 | ALDH1A1 (0.45) | MEN1CYP2C9CYP2C19KMT2ALMNA | |
| SCHEMBL12727318 | 0.72 | EGLN3 (0.74) | EGLN3EGLN1TP53EGLN2MEN1 | |
| SCHEMBL1641768 | 0.72 | EGLN3 (0.74) | EGLN3EGLN1TP53EGLN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089051-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES: PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-24 | — | — | WO | claimed |