Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740148 | 0.92 | TSHR (0.50) | TSHRHTTNPSR1HSD11B1KMT2A | |
| SCHEMBL4739786 | 0.92 | TSHR (0.50) | TSHRHTTNPSR1HSD11B1KMT2A | |
| SCHEMBL4736700 | 0.90 | TSHR (0.58) | TSHRHSD11B1KMT2ALMNAPOLB | |
| SCHEMBL4738255 | 0.90 | TSHR (0.58) | TSHRHSD11B1KMT2ALMNAPOLB | |
| SCHEMBL4741087 | 0.89 | AKR1C3 (0.48) | TSHRHTTHSD11B1KMT2ALMNA | |
| SCHEMBL4736643 | 0.87 | TSHR (0.51) | TSHRHSD11B1KMT2ALMNAMAPT | |
| SCHEMBL4785915 | 0.85 | L3MBTL1 (0.51) | TSHRHSD11B1KMT2ALMNAMAPT | |
| SCHEMBL4738938 | 0.85 | TSHR (0.56) | TSHRHTTNPSR1KMT2ALMNA | |
| SCHEMBL4736686 | 0.84 | HDAC3 (0.50) | TSHRHTTNPSR1HSD11B1POLB | |
| SCHEMBL4741083 | 0.82 | TSHR (0.58) | TSHRHSD11B1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | disclosed |