Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 7/20 | 0.40 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SAT1 | P21673 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232535 | 0.98 | RAD52 (0.44) | CYP2C19CYP1A2CYP2D6RAD52CXCR4 | |
| SCHEMBL18236766 | 0.90 | — | — | |
| SCHEMBL11519285 | 0.85 | RAD52 (0.47) | CYP2C19CYP1A2CYP2D6RAD52CXCR4 | |
| SCHEMBL11522705 | 0.85 | RAD52 (0.47) | CYP2C19CYP1A2CYP2D6RAD52CXCR4 | |
| SCHEMBL20052077 | 0.85 | CXCR4 (0.58) | CYP2C19CYP1A2CXCR4CXCL12SAT1 | |
| SCHEMBL24096072 | 0.82 | SAT1 (0.39) | CYP2C19CYP1A2CYP2D6RAD52CXCR4 | |
| SCHEMBL11522649 | 0.82 | RAD52 (0.50) | RAD52CXCR4CXCL12KDM4EALDH1A1 | |
| SCHEMBL4741840 | 0.82 | RAD52 (0.50) | RAD52CXCR4CXCL12KDM4EALDH1A1 | |
| SCHEMBL17710342 | 0.82 | RAD52 (0.50) | RAD52CXCR4CXCL12KDM4EALDH1A1 | |
| SCHEMBL11437977 | 0.82 | KDM4E (0.44) | CYP2C19CYP1A2CYP2D6RAD52CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008092681-A1 | GHRELIN RECEPTOR MODULATORS | PROSIDION LIMITED (GB) | 2008-08-07 | — | — | WO | disclosed |