Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.52 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.52 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.52 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.52 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.52 |
| ▸ | OGFRL1 | Q5TC84 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.37 |
| ▸ | ASPH | Q12797 | 1/20 | 0.37 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741252 | 0.87 | EGLN1 (0.52) | EGLN1OGFOD1EGLN2EGLN3HIF1AN | |
| SCHEMBL4782873 | 0.76 | EGLN1 (0.63) | EGLN1OGFOD1EGLN2EGLN3HIF1AN | |
| SCHEMBL4991742 | 0.76 | EGLN1 (0.54) | EGLN1OGFOD1EGLN2EGLN3HIF1AN | |
| SCHEMBL4739996 | 0.74 | EGLN1 (0.61) | EGLN1OGFOD1EGLN2EGLN3HIF1AN | |
| SCHEMBL4740150 | 0.72 | MAPT (0.44) | PTGDR2MEN1KMT2A | |
| SCHEMBL3419504 | 0.72 | EGLN1 (0.73) | EGLN1OGFOD1EGLN2EGLN3HIF1AN | |
| SCHEMBL4997472 | 0.70 | EGLN1 (0.57) | EGLN1OGFOD1EGLN2EGLN3HIF1AN | |
| SCHEMBL3419612 | 0.69 | EGLN1 (0.69) | EGLN1OGFOD1EGLN2EGLN3HIF1AN | |
| SCHEMBL3423522 | 0.69 | EGLN1 (1.00) | EGLN1OGFOD1EGLN2EGLN3HIF1AN | |
| SCHEMBL3419112 | 0.69 | EGLN1 (1.00) | EGLN1OGFOD1EGLN2EGLN3HIF1AN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089051-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES: PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-24 | — | — | WO | claimed |