Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.30 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7225783 | 1.00 | EPHX1 (0.37) | EPHX1DPP4ALDH1A1MMP1MMP2 | |
| SCHEMBL1614329 | 0.77 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL18706685 | 0.75 | EPHX1 (0.31) | EPHX1 | |
| SCHEMBL1064167 | 0.74 | — | — | |
| SCHEMBL32677608 | 0.73 | CYP3A4 (0.48) | EPHX1DPP4ALDH1A1 | |
| SCHEMBL32677609 | 0.73 | CYP3A4 (0.48) | EPHX1DPP4ALDH1A1 | |
| SCHEMBL26349710 | 0.73 | CYP3A4 (0.48) | EPHX1DPP4ALDH1A1 | |
| SCHEMBL31355393 | 0.73 | EPHX1 (0.43) | EPHX1DPP4ALDH1A1 | |
| SCHEMBL22609005 | 0.72 | SLC1A3 (0.36) | MMP1MMP2MMP3MMP13 | |
| SCHEMBL22609004 | 0.72 | SLC1A3 (0.36) | MMP1MMP2MMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008098056-A2 | HIGH RELAXIVITY CHELATES | EPIX PHARMACEUTICALS, INC. (US) | 2008-08-14 | — | — | WO | disclosed |