Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740550 | 1.00 | REN (0.55) | RENCYP3A4 | |
| SCHEMBL4740545 | 0.97 | REN (0.54) | RENCYP3A4 | |
| SCHEMBL4806656 | 0.87 | REN (0.61) | RENCYP3A4 | |
| SCHEMBL4806679 | 0.87 | REN (0.61) | RENCYP3A4 | |
| SCHEMBL4806650 | 0.87 | REN (0.61) | RENCYP3A4 | |
| SCHEMBL1751251 | 0.87 | REN (0.56) | RENCYP3A4 | |
| SCHEMBL1751751 | 0.80 | REN (0.59) | RENCYP3A4 | |
| SCHEMBL1751261 | 0.78 | REN (0.50) | RENCYP3A4 | |
| SCHEMBL1751259 | 0.78 | REN (0.50) | RENCYP3A4 | |
| SCHEMBL1751959 | 0.78 | REN (0.50) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981847-A1 | SECONDARY AMINES AS RENIN INHIBITORS | Actelion Pharmaceuticals Ltd. (CH) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007088514-A1 | SECONDARY AMINES AS RENIN INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2007-08-09 | — | — | WO | disclosed |