Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | JAK2 | O60674 | 1/20 | 0.60 |
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | PPARA | Q07869 | 5/20 | 0.57 |
| ▸ | PPARD | Q03181 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.55 |
| ▸ | P4HB | P07237 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 3/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740731 | 1.00 | MAPT (0.62) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL4739589 | 0.87 | ALDH1A1 (0.57) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL4739592 | 0.87 | ALDH1A1 (0.57) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL4741572 | 0.86 | MAPT (0.56) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL4741574 | 0.86 | MAPT (0.56) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL4738112 | 0.83 | ALDH1A1 (0.51) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL4738110 | 0.83 | ALDH1A1 (0.51) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL6362019 | 0.82 | CYP1A1 (0.56) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL4741587 | 0.82 | ALDH1A1 (0.54) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL4741589 | 0.82 | ALDH1A1 (0.54) | MAPTALDH1A1LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087367-A2 | SUBSTITUTED (PHENYLTHIAZOLYL)-PHENYL-PROPAN-1-ONE AND (PHENYLOXAZODYL)-PHENYL-PROPAN-1-ONE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008087367-A2 | SUBSTITUTED (PHENYLTHIAZOLYL)-PHENYL-PROPAN-1-ONE AND (PHENYLOXAZODYL)-PHENYL-PROPAN-1-ONE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |