Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.63 |
| ▸ | IGF1R | P08069 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8862032 | 1.00 | CALM1 (0.63) | CALM1IGF1RALOX15CYP4F2CYP4A11 | |
| SCHEMBL8413383 | 1.00 | CALM1 (0.63) | CALM1IGF1RALOX15CYP4F2CYP4A11 | |
| SCHEMBL1171813 | 0.98 | CALM1 (0.66) | CALM1IGF1RALOX15CYP4F2CYP4A11 | |
| SCHEMBL79113 | 0.92 | CALM1 (0.68) | CALM1IGF1RALOX15CYP4A11TAAR1 | |
| SCHEMBL10571532 | 0.89 | CALM1 (0.69) | CALM1IGF1RALOX15TDP1L3MBTL1 | |
| SCHEMBL17400406 | 0.89 | CALM1 (0.69) | CALM1IGF1RALOX15TDP1L3MBTL1 | |
| SCHEMBL9509173 | 0.89 | CALM1 (0.69) | CALM1IGF1RALOX15TDP1L3MBTL1 | |
| SCHEMBL11007798 | 0.89 | CALM1 (0.69) | CALM1IGF1RALOX15TDP1L3MBTL1 | |
| SCHEMBL28218193 | 0.89 | CALM1 (0.69) | CALM1IGF1RALOX15TDP1L3MBTL1 | |
| SCHEMBL4254058 | 0.87 | CALM1 (0.72) | CALM1IGF1RALOX15TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12398168-B2 | Preparation method of a glycoside compound | SHANGHAI HUTCHISON PHARMACEUTICALS LIMITED (CN) | 2025-08-26 | — | — | US | disclosed |
| US-20220380399-A1 | PREPARATION METHOD OF A GLYCOSIDE COMPOUND | SHANGHAI HUTCHISON PHARMACEUTICALS LIMITED (CN) | 2022-12-01 | — | — | US | disclosed |
| CN-113651729-B | Preparation method of iron-catalyzed 4-aminoalcohol | 西安交通大学 | 2022-10-28 | — | — | CN | disclosed |
| US-11325937-B2 | Glycoside compound and preparation method therefor, composition, application, and intermediate | SHANGHAI HUTCHISON PHARMACEUTICALS LIMITED (CN) | 2022-05-10 | — | — | US | disclosed |
| CN-113651729-A | Preparation method of iron-catalyzed 4-aminoalcohol | 西安交通大学 | 2021-11-16 | — | — | CN | disclosed |
| WO-2021139621-A1 | METHOD FOR PREPARING GLYCOSIDE COMPOUND | 上海和黄药业有限公司 | 2021-07-15 | — | — | WO | disclosed |
| CN-112851456-A | Method for preparing olefin compound under alkaline condition | 扬州工业职业技术学院 | 2021-05-28 | — | — | CN | disclosed |
| EP-3819303-A1 | GLYCOSIDE COMPOUND AND PREPARATION METHOD THEREFOR, COMPOSITION, APPLICATION, AND INTERMEDIATE | Shanghai Hutchison Pharmaceuticals Limited (CN) | 2021-05-12 | — | — | EP | disclosed |
| US-20210115082-A1 | GLYCOSIDE COMPOUND AND PREPARATION METHOD THEREFOR, COMPOSITION, APPLICATION, AND INTERMEDIATE | SHANGHAI HUTCHISON PHARMACEUTICALS LIMITED (CN) | 2021-04-22 | — | — | US | disclosed |
| WO-2008081096-A2 | QUINOLINYL DERIVATIVES, METHOD FOR PREPARING SAME, PHARMACEUTIC COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS HYPOGLYCEMIANT AND HYPOLIPEMIANT AGENTS | LES LABORATOIRES SERVIER (FR) | 2008-07-10 | — | — | WO | disclosed |
| US-20040198746-A1 | Sodium channel blockers | PARION SCIENCES, INC. (US) | 2004-10-07 | — | — | US | disclosed |
| US-20040198745-A1 | Sodium channel blockers | PARION SCIENCES, INC. (US) | 2004-10-07 | — | — | US | disclosed |
| US-20040198747-A1 | Sodium channel blockers | PARION SCIENCES, INC. (US) | 2004-10-07 | — | — | US | disclosed |
| US-20030195160-A1 | Sodium channel blockers | CYFI, INC. | 2003-10-16 | — | — | US | disclosed |
| WO-2003070184-A2 | SODIUM CHANNEL BLOCKERS | JOHNSON MICHAEL R (US) | 2003-08-28 | — | — | WO | disclosed |
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |
| EP-0162208-B1 | NOVEL N-SUBSTITUTED 3,4-DIHYDROPYRIMIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1989-11-23 | — | — | EP | disclosed |
| US-4683234-A | HYPOTENSIVE AGENTS, ANTI-ANGINA | SUNTORY LIMITED (JP) | 1987-07-28 | — | — | US | disclosed |
| EP-0162208-A2 | Novel N-substituted 3,4-dihydropyrimidine derivatives, processes for preparing them and pharmaceutical compositions | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195160-A1 | Sodium channel blockers | HCN4, SCN2B, SCN5A | CALM1 548/4885IGF1R 4865/4885ALOX15 2153/4885 |
| US-20040198747-A1 | Sodium channel blockers | HCN4, SCN2B, SCN5A | CALM1 548/4885IGF1R 4865/4885ALOX15 2153/4885 |
| US-12398168-B2 | Preparation method of a glycoside compound | GALE, ST6GAL1, MGAM | CALM1 4863/4885IGF1R 4200/4885ALOX15 3217/4885 |
| US-20220380399-A1 | PREPARATION METHOD OF A GLYCOSIDE COMPOUND | GALE, ST6GAL1, MGAM | CALM1 4863/4885IGF1R 4200/4885ALOX15 3217/4885 |
| US-11325937-B2 | Glycoside compound and preparation method therefor, composition, application, and intermediate | VEGFA, FLT4, FLT1 | CALM1 3278/4885IGF1R 86/4885ALOX15 1291/4885 |
| US-20040198745-A1 | Sodium channel blockers | SCN2B, SCN4A, SCN1B | CALM1 836/4885IGF1R 4370/4885ALOX15 3938/4885 |
| US-20040198746-A1 | Sodium channel blockers | HCN4, SCN2B, SCN5A | CALM1 548/4885IGF1R 4865/4885ALOX15 2153/4885 |
| US-20210115082-A1 | GLYCOSIDE COMPOUND AND PREPARATION METHOD THEREFOR, COMPOSITION, APPLICATION, AND INTERMEDIATE | VEGFA, FLT4, FLT1 | CALM1 3278/4885IGF1R 86/4885ALOX15 1291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.