Phosphoric Acid

Phosphoric Acid

SCHEMBL474083

O.O=P([O-])(O)O.O=P([O-])(O)O.O=P([O-])(O)O.[H+].[H+].[Na+]

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC34A1 Q06495 1/20 0.67
KDM4E B2RXH2 2/20 0.44
CYP2C19 P33261 1/20 0.44
KMT2A Q03164 1/20 0.44
LMNA P02545 2/20 0.44
CA2 P00918 1/20 0.36
CA1 P00915 2/20 0.35
CA4 P22748 2/20 0.35
CA5A P35218 2/20 0.35
CA5B Q9Y2D0 2/20 0.35
MMP2 P08253 1/20 0.31
THRB P10828 1/20 0.31
MAPK1 P28482 1/20 0.31
HSD17B10 Q99714 1/20 0.31
FDPS P14324 1/20 0.31
BLM P54132 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL15612335 1.00 SLC34A1 (0.67) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL17941716 0.96 SLC34A1 (0.61) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL40491 0.95
Phosphoric Acid SCHEMBL101070 0.95
Phosphoric Acid SCHEMBL28894407 0.95 SLC34A1 (0.73) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL6155231 0.95
Phosphoric Acid SCHEMBL4731817 0.95
Phosphoric Acid SCHEMBL8972786 0.95 SLC34A1 (0.73) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL14656197 0.95 SLC34A1 (0.73) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL653726 0.95 SLC34A1 (0.73) SLC34A1KDM4ECYP2C19KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4098267-A1 MEDICINAL COMPOSITION COMPRISING DENTAL PULP-DERIVED CELLS JCR Pharmaceuticals Co., Ltd. (JP) 2022-12-07 EP disclosed
EP-3219322-A1 MUSCULAR DYSTROPHY THERAPEUTIC AGENT CONTAINING PLURIPOTENT STEM CELLS DERIVED FROM DENTAL PULP JCR Pharmaceuticals CO., LTD. (JP) 2017-09-20 EP disclosed
EP-2832850-B1 METHOD FOR PRODUCING PLURIPOTENT STEM CELLS DERIVED FROM DENTAL PULP JAPAN CHEM RES (JP) 2017-09-06 EP disclosed
CN-101264338-B Calcium phosphate cement HOWMEDICA LEIBINGER INC 2012-05-09 CN disclosed
EP-1712245-B1 Calcium phosphate cement HOWMEDICA OSTEONICS CORP (US) 2012-02-01 EP disclosed
EP-2260877-A1 Calcium phosphate cement STRYKER CORPORATION (US) 2010-12-15 EP disclosed
CN-100460021-C Calcium phosphate cement HOWMEDICAL LEIBINGER INC D B A (US) 2009-02-11 CN disclosed
CN-101264338-A Calcium phosphate cement HOWMEDICA LEIBINGER INC (US) 2008-09-17 CN disclosed
EP-1938844-A2 Calcium phosphate cement Howmedica Leibinger Inc. (US) 2008-07-02 EP disclosed
EP-1712245-A2 Calcium phosphate cement Howmedica Leibinger Inc. (US) 2006-10-18 EP disclosed
US-20060225621-A1 Injectable calcium phosphate cement HOWMEDICA LEIBINGER INC. (US) 2006-10-12 US disclosed
CN-1844010-A Calcium phosphate cement HOWMEDICAL LEIBINGER INC D B A (US) 2006-10-11 CN disclosed