Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.36 |
| ▸ | EGFR | P00533 | 4/20 | 0.36 |
| ▸ | KDR | P35968 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | LTK | P29376 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4238745 | 0.90 | MCHR1 (0.42) | MCHR1EGFRKDRSMN1; SMN2NPSR1 | |
| SCHEMBL4240513 | 0.87 | MCHR1 (0.40) | MCHR1SMN1; SMN2NPSR1MAPTALDH1A1 | |
| SCHEMBL4236573 | 0.86 | MCHR1 (0.45) | MCHR1EGFRKDRSMN1; SMN2NPSR1 | |
| SCHEMBL4787885 | 0.86 | MCHR1 (0.37) | MCHR1EGFRKDRSMN1; SMN2NPSR1 | |
| SCHEMBL4234129 | 0.84 | MCHR1 (0.42) | MCHR1EGFRKDRSMN1; SMN2NPSR1 | |
| SCHEMBL4233894 | 0.84 | MCHR1 (0.47) | MCHR1EGFRKDRSMN1; SMN2NPSR1 | |
| SCHEMBL4236062 | 0.84 | MCHR1 (0.47) | MCHR1EGFRKDRSMN1; SMN2NPSR1 | |
| SCHEMBL4229397 | 0.83 | MCHR1 (0.44) | MCHR1EGFRKDRSMN1; SMN2NPSR1 | |
| SCHEMBL4859535 | 0.82 | CSF1R (0.33) | MCHR1KDRSMN1; SMN2METMAPT | |
| SCHEMBL4367942 | 0.82 | SMN1; SMN2 (0.40) | MCHR1SMN1; SMN2NPSR1METMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |