Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 6/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | LCK | P06239 | 3/20 | 0.30 |
| ▸ | MET | P08581 | 3/20 | 0.30 |
| ▸ | TEK | Q02763 | 3/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4233984 | 0.85 | KDR (0.38) | KDRMAPTDGAT1LMNARXFP1 | |
| SCHEMBL4240513 | 0.85 | MCHR1 (0.40) | MCHR1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL4228379 | 0.82 | MCHR1 (0.41) | FGFR1MCHR1RAB9AMAPT | |
| SCHEMBL4234129 | 0.82 | MCHR1 (0.42) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL4740848 | 0.82 | MCHR1 (0.36) | PDGFRAFGFR1KDRMCHR1MAPT | |
| SCHEMBL4226703 | 0.81 | SMN1; SMN2 (0.39) | FGFR1KDRMCHR1MAPTSMN1; SMN2 | |
| SCHEMBL4236573 | 0.79 | MCHR1 (0.45) | KDRMCHR1NPC1RAB9AMAPT | |
| SCHEMBL4744081 | 0.79 | MCHR1 (0.38) | FGFR1MCHR1MAPT | |
| SCHEMBL4237517 | 0.79 | CCR3 (0.45) | FGFR1KDRMCHR1NPC1RAB9A | |
| SCHEMBL4686192 | 0.78 | CCR3 (0.41) | CSF1RFLT3PDGFRBKITPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | claimed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | claimed |