Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 8/20 | 0.39 |
| ▸ | DRD2 | P14416 | 7/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741160 | 0.84 | ADRB2 (0.44) | ADRB2ADRB1ADRA1DDRD2 | |
| SCHEMBL4784295 | 0.75 | ADRB2 (0.44) | ADRB2ADRB1ADRA1D | |
| SCHEMBL4786691 | 0.71 | ADRB2 (0.59) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL3685868 | 0.65 | ADRB2 (0.49) | ADRB2ADRB1DRD2 | |
| SCHEMBL1801831 | 0.64 | ADRB2 (0.65) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL1803443 | 0.63 | ADRB2 (0.57) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL1801168 | 0.63 | ADRB2 (0.57) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL1802891 | 0.62 | ADRB2 (0.70) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL9312206 | 0.62 | KMT2A (0.67) | — | |
| Hydrochloric Acid SCHEMBL6183356 | 0.62 | ADRB2 (0.65) | ADRB2ADRB1ADRA1DDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096129-A1 | NITROGEN CONTAINING HETROCYCLIC COMPOUNDS USEFUL AS BIFUNCTIONAL MODULATORS OF M3 RECEPTORS AND BETA- 2 RECEPTORS | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |