Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 7/20 | 0.34 |
| ▸ | MAOA | P21397 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA4 | P22748 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741646 | 0.88 | GSTP1 (0.41) | GSTP1MAOBMAOAACHEP2RX3 | |
| SCHEMBL4680859 | 0.78 | GSTP1 (0.37) | GSTP1MAOBMAOALMNAACHE | |
| SCHEMBL28397137 | 0.76 | GSTP1 (0.45) | GSTP1MAOBMAOAACHECA12 | |
| SCHEMBL28397565 | 0.76 | GSTP1 (0.45) | GSTP1MAOBMAOAACHECA12 | |
| SCHEMBL4738930 | 0.75 | HTR2C (0.38) | MAOBLMNACA12CA9CA1 | |
| SCHEMBL4734667 | 0.75 | HTT (0.35) | MAOBCA12CA9CA1CA2 | |
| SCHEMBL15747176 | 0.73 | MAOB (0.44) | GSTP1MAOBMAOAACHEP2RX3 | |
| SCHEMBL4734966 | 0.72 | PARP10 (0.40) | — | |
| SCHEMBL3204571 | 0.71 | GSTP1 (0.52) | GSTP1MAOBMAOAACHECA12 | |
| SCHEMBL28399593 | 0.70 | GSTP1 (0.39) | GSTP1MAOBMAOAACHECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343775-B1 | PIPERAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-06-04 | — | — | EP | claimed |