Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3175221 | 0.84 | CYP2C19 (0.80) | CYP2C19CYP3A4CYP2D6POLBMEN1 | |
| SCHEMBL4924033 | 0.83 | CYP3A4 (0.52) | CYP2C19CYP3A4CYP2D6POLBMEN1 | |
| SCHEMBL23291288 | 0.82 | EPHX2 (0.60) | ALDH1A1SMN1; SMN2KDM4EMAPK1SIGMAR1 | |
| SCHEMBL3179723 | 0.81 | CYP2C19 (0.76) | CYP2C19CYP3A4CYP2D6POLBMEN1 | |
| SCHEMBL14068495 | 0.80 | CYP2C19 (0.70) | CYP2C19CYP3A4CYP2D6POLBMEN1 | |
| SCHEMBL3704422 | 0.80 | CYP2C19 (0.74) | CYP2C19CYP3A4CYP2D6POLBMEN1 | |
| SCHEMBL3181015 | 0.80 | CYP2C19 (0.74) | CYP2C19CYP3A4CYP2D6POLBMEN1 | |
| Water SCHEMBL28295097 | 0.79 | CYP2C19 (0.72) | CYP2C19CYP3A4CYP2D6POLBMEN1 | |
| SCHEMBL76649 | 0.78 | GAA (0.68) | POLBALDH1A1SMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL3173768 | 0.78 | CYP2C19 (0.67) | CYP2C19CYP3A4CYP2D6POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109154-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |