Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 7/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523560 | 0.99 | CYP19A1 (0.35) | KCNH2MEN1CYP19A1KDM4EALDH1A1 | |
| SCHEMBL523559 | 0.99 | CYP19A1 (0.35) | KCNH2MEN1CYP19A1KDM4EALDH1A1 | |
| Bromide SCHEMBL1179776 | 0.98 | CYP19A1 (0.35) | KCNH2MEN1CYP19A1KDM4EALDH1A1 | |
| Bromide SCHEMBL1179774 | 0.98 | CYP19A1 (0.35) | KCNH2MEN1CYP19A1KDM4EALDH1A1 | |
| SCHEMBL4743192 | 0.95 | CYP19A1 (0.36) | KCNH2MEN1CYP19A1KDM4EALDH1A1 | |
| SCHEMBL4743190 | 0.95 | CYP19A1 (0.36) | KCNH2MEN1CYP19A1KDM4EALDH1A1 | |
| SCHEMBL4742435 | 0.90 | MEN1 (0.38) | MEN1KMT2A | |
| SCHEMBL4742433 | 0.90 | MEN1 (0.38) | MEN1KMT2A | |
| SCHEMBL1109901 | 0.90 | CYP19A1 (0.39) | KCNH2MEN1CYP19A1KMT2ALMNA | |
| SCHEMBL1109903 | 0.90 | CYP19A1 (0.39) | KCNH2MEN1CYP19A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | claimed |
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |