Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 15/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4742435 | 1.00 | MEN1 (0.38) | MEN1KMT2AARNPY2R | |
| SCHEMBL523560 | 0.91 | CYP19A1 (0.35) | MEN1KMT2A | |
| SCHEMBL523559 | 0.91 | CYP19A1 (0.35) | MEN1KMT2A | |
| Bromide SCHEMBL1179774 | 0.90 | CYP19A1 (0.35) | MEN1KMT2A | |
| Bromide SCHEMBL1179776 | 0.90 | CYP19A1 (0.35) | MEN1KMT2A | |
| SCHEMBL4741472 | 0.90 | KCNH2 (0.35) | MEN1KMT2A | |
| SCHEMBL4782438 | 0.88 | MEN1 (0.38) | MEN1KMT2AARNPY2R | |
| SCHEMBL4743190 | 0.86 | CYP19A1 (0.36) | MEN1KMT2A | |
| SCHEMBL4743192 | 0.86 | CYP19A1 (0.36) | MEN1KMT2A | |
| SCHEMBL1109903 | 0.86 | CYP19A1 (0.39) | MEN1KMT2ANPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | claimed |
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |