Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6245912 | 0.95 | MRGPRX4 (0.52) | CYP11B2CYP11B1NSD2NSD3MRGPRX4 | |
| SCHEMBL13223331 | 0.85 | CYP11B1 (0.51) | CYP11B2CYP11B1NSD2NSD3MRGPRX4 | |
| SCHEMBL3915058 | 0.84 | CYP11B1 (0.51) | CYP11B2CYP11B1NSD2NSD3MRGPRX4 | |
| SCHEMBL3915224 | 0.83 | MRGPRX4 (0.52) | CYP11B2CYP11B1NSD2NSD3MRGPRX4 | |
| SCHEMBL30580547 | 0.82 | AR (0.50) | CYP11B2CYP11B1NSD2NSD3MRGPRX4 | |
| SCHEMBL11037750 | 0.81 | ALDH1A1 (0.50) | CYP11B2CYP11B1NSD2NSD3MRGPRX4 | |
| SCHEMBL3918849 | 0.81 | MRGPRX4 (0.51) | CYP11B2CYP11B1NSD2NSD3MRGPRX4 | |
| SCHEMBL1714514 | 0.81 | CYP11B1 (0.44) | CYP11B2CYP11B1TRPV4MAOBMAOA | |
| SCHEMBL6246944 | 0.80 | MAOB (0.54) | CYP11B2CYP11B1NSD2NSD3MRGPRX4 | |
| SCHEMBL1180075 | 0.79 | KDM4E (0.62) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |