Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527603 | 0.97 | NR1H4 (0.45) | NR1H4ELANECTSD | |
| SCHEMBL4729688 | 0.95 | NR1H4 (0.43) | NR1H4ELANECTSD | |
| SCHEMBL5691316 | 0.94 | NR1H4 (0.45) | NR1H4ELANECTSD | |
| SCHEMBL4596921 | 0.94 | NR1H4 (0.50) | NR1H4ELANECTSD | |
| SCHEMBL4783554 | 0.92 | NR1H4 (0.43) | NR1H4ELANECTSD | |
| SCHEMBL6629929 | 0.92 | NR1H4 (0.45) | NR1H4ELANECTSD | |
| SCHEMBL4782192 | 0.92 | NR1H4 (0.42) | NR1H4ELANECTSD | |
| SCHEMBL5327298 | 0.91 | NR1H4 (0.45) | NR1H4ELANECTSD | |
| SCHEMBL4662900 | 0.91 | NR1H4 (0.42) | NR1H4ELANECTSD | |
| SCHEMBL5707135 | 0.91 | NR1H4 (0.42) | NR1H4ELANECTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885694-A2 | 4-BIARYLYL-1-PHENYLAZETIDIN-2-ONES | Microbia, Inc. (US) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006124713-A2 | 4-BIARYLYL-1-PHENYLAZETIDIN-2-ONES | MICROBIA, INC. (US) | 2006-11-23 | — | — | WO | disclosed |
| EP-1458677-A1 | 3-PHENYL-2-ARYLALKYLTHIOPROPIONIC ACID DERIVATIVES AS SELECTIVE AGONISTS OF PPAR-ALPHA | Astrazeneca AB (SE) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051826-A1 | 3-PHENYL-2-ARYLALKYLTHIOPROPIONIC ACID DERIVATIVES AS SELECTIVE AGONISTS OF PPAR-ALPHA | ASTRAZENECA AB (SE) | 2003-06-26 | — | — | WO | disclosed |