Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 3/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5691316 | 0.94 | NR1H4 (0.45) | NR1H4ELANECTSD | |
| SCHEMBL4741522 | 0.92 | NR1H4 (0.44) | NR1H4ELANECTSD | |
| SCHEMBL5707135 | 0.92 | NR1H4 (0.42) | NR1H4ELANECTSD | |
| SCHEMBL4662900 | 0.92 | NR1H4 (0.42) | NR1H4ELANECTSD | |
| SCHEMBL4782192 | 0.92 | NR1H4 (0.42) | NR1H4ELANECTSD | |
| SCHEMBL4729688 | 0.91 | NR1H4 (0.43) | NR1H4ELANECTSD | |
| SCHEMBL5327298 | 0.91 | NR1H4 (0.45) | NR1H4ELANECTSD | |
| SCHEMBL6629929 | 0.91 | NR1H4 (0.45) | NR1H4ELANECTSD | |
| SCHEMBL3853019 | 0.90 | NR1H4 (0.41) | NR1H4ELANECTSD | |
| SCHEMBL6527603 | 0.90 | NR1H4 (0.45) | NR1H4ELANECTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008039829-A2 | DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2008-04-03 | — | — | WO | disclosed |